Flavone

Flavone

SCHEMBL27686205

Cc1ccccc1C.O=c1cc(-c2ccccc2)oc2ccccc12

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 10/20 0.84
PARP1 P09874 4/20 0.84
TNKS2 Q9H2K2 4/20 0.84
HPGD P15428 4/20 0.84
RAB9A P51151 4/20 0.84
SMN1; SMN2 Q16637 4/20 0.84
TP53 P04637 3/20 0.84
CYP3A4 P08684 3/20 0.84
NPC1 O15118 3/20 0.84
GABRP O00591 3/20 0.84
GABRD O14764 3/20 0.84
GABRA1 P14867 3/20 0.84
GABRB1 P18505 3/20 0.84
GABRG2 P18507 3/20 0.84
GABRB3 P28472 3/20 0.84
GABRA5 P31644 3/20 0.84
GABRA3 P34903 3/20 0.84
GABRA2 P47869 3/20 0.84
GABRB2 P47870 3/20 0.84
GABRA4 P48169 3/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavone SCHEMBL15676601 0.92 TNKS (1.00) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL28248986 0.92 TNKS (1.00) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL30542161 0.92 TNKS (1.00) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL31316377 0.92 TNKS (1.00) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL18879 0.92 TNKS (1.00) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL27560931 0.90 TNKS (0.85) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL23645524 0.90 TNKS (0.90) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL9530678 0.90 TNKS (0.96) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL3090011 0.90 TNKS (0.96) TNKSPARP1TNKS2HPGDRAB9A
Flavone SCHEMBL6908621 0.90 TNKS (0.96) TNKSPARP1TNKS2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106420919-A Preparation method and application of Nepeta bracteatatotal flavonoids 新疆医科大学 2017-02-22 CN disclosed
CN-105748539-A Juniperus sabina total flavonoid extract as well as preparation method and application thereof 新疆维吾尔自治区药物研究所 2016-07-13 CN disclosed
CN-102247424-B Application of abrus herb general flavone for treating and preventing gastric ulcer UNIV CHINA PHARMA 2013-06-12 CN disclosed
CN-102247424-A Application of abrus herb general flavone for treating and preventing gastric ulcer UNIV CHINA PHARMA 2011-11-23 CN disclosed
CN-1899341-B American goldenrod herb total flavone extract and its preparing method and use LINSAIJIAO BIOLOG SCIENCE AND TECHNOLOGY DEV CO LTD SHANGHAI 2010-05-26 CN disclosed
CN-101069703-A Medicine for treating acute, chronic pharyngitis, acute, chronic tonsillitis and preparing method LING PEIXUE (CN) 2007-11-14 CN disclosed
CN-1899341-A American goldenrod herb total flavone extract and its preparing method and use LINSAIJIAO BIOLOG SCIENCE AND (CN) 2007-01-24 CN disclosed