Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 10/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686315 | 0.86 | GSK3B (0.36) | VNN1GSK3BPPARGGRM5MAPK14 | |
| SCHEMBL9077010 | 0.76 | PLA2G4B (0.54) | — | |
| SCHEMBL481111 | 0.74 | VNN1 (0.48) | VNN1GSK3B | |
| SCHEMBL27705287 | 0.74 | MAOB (0.36) | MAOB | |
| SCHEMBL13138798 | 0.72 | VNN1 (0.46) | VNN1GRM5MAPK14BRAF | |
| SCHEMBL9078419 | 0.71 | HPGD (0.66) | VNN1GSK3B | |
| SCHEMBL7780410 | 0.71 | VNN1 (0.63) | VNN1GSK3BMAPK14 | |
| SCHEMBL11574251 | 0.70 | CYP2C8 (0.62) | — | |
| SCHEMBL22169839 | 0.70 | MRGPRX4 (0.48) | VNN1GSK3BGRM5MAPK14BRAF | |
| SCHEMBL4709037 | 0.70 | VNN1 (0.51) | VNN1GSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955470-A | Glutamate receptor potentiators | LILLY CO ELI | 2011-01-26 | — | — | CN | disclosed |
| CN-101061106-B | Glutamate receptor potentiators | LILLY CO ELI | 2010-09-29 | — | — | CN | disclosed |
| CN-101061106-A | Glutamate receptor potentiators | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |