Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874253 | 0.90 | HPGD (0.44) | HSPA5ALDH1A1GAARAB9ATSHR | |
| SCHEMBL8264711 | 0.78 | CTSK (0.50) | HDAC1ALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL2070869 | 0.76 | CTSK (0.49) | HDAC1HDAC6HTTCTSK | |
| SCHEMBL21937840 | 0.76 | GAA (0.51) | ALDH1A1GAARAB9ATSHRHPGD | |
| SCHEMBL6522516 | 0.76 | KMT2A (0.44) | HDAC1HDAC6ALDH1A1RAB9ALMNA | |
| SCHEMBL6522512 | 0.76 | KMT2A (0.44) | HDAC1HDAC6ALDH1A1RAB9ALMNA | |
| SCHEMBL2072888 | 0.75 | SIRT2 (0.62) | ALDH1A1CTSKCTSL | |
| SCHEMBL7453813 | 0.75 | RAB9A (0.54) | HSPA5HDAC1ALDH1A1GAARAB9A | |
| SCHEMBL7453809 | 0.75 | RAB9A (0.54) | HSPA5HDAC1ALDH1A1GAARAB9A | |
| SCHEMBL27793143 | 0.75 | C3AR1 (0.53) | ALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133024-A | Amide derivatives as histone deacetylase inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-02-27 | — | — | CN | disclosed |