SCHEMBL27686387

SCHEMBL27686387

CCCCC(C)CC.CCc1c(C(=O)O)cccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RECQL P46063 1/20 0.42
CA2 P00918 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.40
POLB P06746 2/20 0.38
LMNA P02545 1/20 0.38
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 1/20 0.38
CLCN2 P51788 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
CNR2 P34972 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27667347 0.91 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1KMT2ARECQL
Phthalic Acid SCHEMBL7129666 0.87 ALDH1A1 (0.56) ALDH1A1KDM4EMEN1KMT2ARECQL
SCHEMBL27667455 0.82 CLCN2 (0.44) ALDH1A1KDM4EMEN1KMT2ARECQL
Salicylic Acid SCHEMBL6132155 0.82 ALDH1A1 (0.55) ALDH1A1KDM4EMEN1KMT2ARECQL
SCHEMBL1355391 0.80 ALDH1A1 (0.52) ALDH1A1KDM4ECA2TSHRCA12
SCHEMBL28411582 0.79 KDM4E (0.42) ALDH1A1KDM4ECA2CA12CA9
SCHEMBL28045256 0.79 ALDH1A1 (0.55) ALDH1A1KDM4EMEN1KMT2ARECQL
SCHEMBL28134185 0.77 CA12 (0.43) ALDH1A1KDM4EMEN1KMT2ARECQL
SCHEMBL11422395 0.77 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1KMT2ARECQL
SCHEMBL28117846 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EMEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100569754-C Have the synthetic and application of antitumour activity as the serial ion liquid of drug candidate CHANGCHUN APPLIED CHEMISTRY (CN) 2009-12-16 CN disclosed
CN-1970543-A Synthesis and uses of serial ion liquid as candidate drug with anticancer activity CHANGCHUN APPLIED CHEMISTRY (CN) 2007-05-30 CN disclosed