SCHEMBL27667347

SCHEMBL27667347

CCCC(C)CC.CCc1c(C(=O)O)cccc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 2/20 0.39
CLCN2 P51788 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RECQL P46063 1/20 0.38
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
ALB P02768 1/20 0.36
MMP2 P08253 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.36
GPR88 Q9GZN0 2/20 0.35
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686387 0.91 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL27667455 0.84 CLCN2 (0.44) ALDH1A1KDM4EHPGDHSD17B10POLB
SCHEMBL1355391 0.82 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDHSD17B10CLCN2
SCHEMBL28134185 0.80 CA12 (0.43) ALDH1A1KDM4EHPGDHSD17B10POLB
Phthalic Acid SCHEMBL7129666 0.77 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL28411582 0.76 KDM4E (0.42) ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL5593056 0.75 CLCN2 (0.45) ALDH1A1KDM4EHPGDHSD17B10CLCN2
SCHEMBL10821860 0.75 HMGB1 (0.50) ALDH1A1KDM4EHPGDHSD17B10CLCN2
SCHEMBL578127 0.75 CLCN2 (0.56) ALDH1A1KDM4EHPGDHSD17B10CLCN2
SCHEMBL14497916 0.75 GABRA1 (0.50) ALDH1A1KDM4EHPGDHSD17B10CLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100569754-C Have the synthetic and application of antitumour activity as the serial ion liquid of drug candidate CHANGCHUN APPLIED CHEMISTRY (CN) 2009-12-16 CN disclosed
CN-1970543-A Synthesis and uses of serial ion liquid as candidate drug with anticancer activity CHANGCHUN APPLIED CHEMISTRY (CN) 2007-05-30 CN disclosed