Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423792 | 0.83 | MIF (0.42) | MEN1KMT2A | |
| SCHEMBL1880595 | 0.81 | CA12 (0.44) | PPARAPPARGCYP3A4MAPTCYP2C19 | |
| SCHEMBL9784096 | 0.75 | ACACB (0.46) | PPARAPPARGACACBELANEABCB1 | |
| SCHEMBL319906 | 0.73 | PPARA (0.63) | PPARAPPARGACACBELANEEPHX2 | |
| SCHEMBL11218542 | 0.73 | PPARA (0.46) | PPARAPPARGACACBELANEMEN1 | |
| SCHEMBL19244302 | 0.72 | ESR1 (0.51) | THRBMEN1CYP1A2MAPTKMT2A | |
| SCHEMBL19244300 | 0.72 | ESR1 (0.51) | THRBMEN1CYP1A2MAPTKMT2A | |
| SCHEMBL9848686 | 0.72 | PPARA (0.47) | PPARAPPARGACACBABCB1MAPT | |
| SCHEMBL13970013 | 0.72 | SMN1; SMN2 (0.45) | PPARAPPARGEPHX2NR1H4MEN1 | |
| SCHEMBL29137262 | 0.72 | ALDH1A1 (0.62) | PPARAPPARGACACBMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133070-A | Novel phosphinic acid amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2008-02-27 | — | — | CN | disclosed |