Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745106 | 0.91 | GAA (0.37) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL689242 | 0.88 | GAA (0.44) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL11204791 | 0.83 | GAA (0.46) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL10391922 | 0.82 | KDM4E (0.54) | MAPTLMNAKMT2AHSD17B10KDM4E | |
| SCHEMBL6371242 | 0.82 | DRD2 (0.42) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL10787248 | 0.81 | GAA (0.44) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL29163224 | 0.79 | ATM (0.46) | HSD17B10ALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL29409819 | 0.78 | TDP1 (0.51) | GAAMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL689262 | 0.78 | GAA (0.47) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL28057308 | 0.76 | POLB (0.46) | GAAMAPTLMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |