Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28791674 | 0.85 | CHRNA1 (0.37) | TYRLMNAPTGS1TRPA1CACNA1C | |
| SCHEMBL27711085 | 0.82 | LMNA (0.39) | TYRLMNAPTGS1TRPA1CACNA1C | |
| SCHEMBL16346007 | 0.81 | S1PR1 (0.39) | S1PR1TYRLMNAPTGS1TRPA1 | |
| SCHEMBL27799748 | 0.79 | S1PR1 (0.38) | S1PR1TYRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4434983 | 0.79 | PARP1 (0.41) | TYRLMNATSHR | |
| SCHEMBL28024314 | 0.79 | GAA (0.45) | TYRLMNATSHRALDH1A1MEN1 | |
| SCHEMBL27776659 | 0.79 | CA12 (0.40) | TYRALDH1A1POLBMEN1GAA | |
| SCHEMBL1762674 | 0.77 | LMNA (0.58) | S1PR1TYRLMNAPTGS1TRPA1 | |
| SCHEMBL18942465 | 0.77 | AKR1C3 (0.45) | LMNAPTGS1TRPA1CACNA1CPTGS2 | |
| SCHEMBL27562953 | 0.77 | CYP3A4 (0.41) | S1PR1TYRLMNAPTGS1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026988-B | 3-substituted propanamines | SK HOLDINGS CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-102026988-A | 3-substituted propanamines | SK HOLDINGS CO LTD | 2011-04-20 | — | — | CN | disclosed |
| CN-101065366-A | Dibenzyl amine compounds and derivatives | PFIZER PROD INC (US) | 2007-10-31 | — | — | CN | disclosed |