Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829817 | 0.82 | ALDH1A1 (0.45) | TYRALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL26968200 | 0.79 | S1PR1 (0.33) | S1PR1ALDH1A1 | |
| SCHEMBL2701208 | 0.79 | AKR1C3 (0.40) | S1PR1TYRALDH1A1LMNAHTT | |
| SCHEMBL27686754 | 0.79 | S1PR1 (0.42) | S1PR1TYRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1506620 | 0.78 | S1PR1 (0.46) | S1PR1TYRALDH1A1ABL1LMNA | |
| SCHEMBL27753244 | 0.78 | APP (0.41) | S1PR1TYR | |
| SCHEMBL4434983 | 0.78 | PARP1 (0.41) | TYRLMNA | |
| SCHEMBL28024314 | 0.78 | GAA (0.45) | TYRALDH1A1LMNAHTTMET | |
| SCHEMBL27776659 | 0.78 | CA12 (0.40) | TYRALDH1A1HTT | |
| SCHEMBL30457919 | 0.76 | S1PR1 (0.41) | S1PR1ABL1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952260-B | 4, 5-dihydro-oxazol-2-yl amine derivatives | HOFFMANN LA ROCHE | 2013-02-13 | — | — | CN | disclosed |
| CN-101952260-A | 4, 5-dihydro-oxazol-2-ylamine derivs | HOFFMANN LA ROCHE | 2011-01-19 | — | — | CN | disclosed |