Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SCN1A | P35498 | 3/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.62 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPRF | P10586 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPA | Q15257 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396552 | 0.97 | TSHR (0.69) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL1665510 | 0.95 | TSHR (0.61) | TSHRSCN1ASCN2ASCN3ALMNA | |
| Bicarbonate SCHEMBL27449726 | 0.95 | TSHR (0.67) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL3230316 | 0.90 | TSHR (0.65) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL29500171 | 0.90 | TSHR (0.65) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL27686775 | 0.89 | TSHR (0.59) | TSHRSCN1ASCN2ASCN3ALMNA | |
| Bicarbonate SCHEMBL5706047 | 0.89 | TSHR (0.62) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL8606461 | 0.89 | TSHR (0.62) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL10476975 | 0.87 | TSHR (0.61) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL8873262 | 0.87 | TSHR (0.61) | TSHRSCN1ASCN2ASCN3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087752-B | Novel ligands that modulate RAR receptors, and use thereof in human medicine and in cosmetics | GALDERMA RES & DEV | 2011-11-16 | — | — | CN | disclosed |
| CN-101087752-A | Novel ligands that modulate RAR receptors, and use thereof in human medicine and in cosmetics | GALDERMA RES & DEV (FR) | 2007-12-12 | — | — | CN | disclosed |