Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | SCN1A | P35498 | 3/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500171 | 0.87 | TSHR (0.65) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL3230316 | 0.87 | TSHR (0.65) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL27686802 | 0.87 | TSHR (0.65) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL396552 | 0.87 | TSHR (0.69) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL8606461 | 0.86 | TSHR (0.62) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| Bicarbonate SCHEMBL27449726 | 0.85 | TSHR (0.67) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL1665510 | 0.85 | TSHR (0.61) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL8873262 | 0.84 | TSHR (0.61) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL7441914 | 0.84 | ALDH1A1 (0.61) | TSHRALDH1A1HSD17B10SCN1ASCN2A | |
| SCHEMBL8601174 | 0.84 | SLC6A4 (0.69) | TSHRALDH1A1HSD17B10SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564960-A1 | Imidazopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |