SCHEMBL27687136

SCHEMBL27687136

Cc1c(-c2ccc(N)cc2)ccc(N(C)C)c1C.Cc1c(-c2ccc(N)cc2)ccc(N(C)C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 2/20 0.40
MAPK1 P28482 2/20 0.40
ALOX15 P16050 1/20 0.40
DHFR P00374 1/20 0.35
ACHE P22303 2/20 0.34
CHEK1 O14757 2/20 0.33
LIMK1 P53667 2/20 0.33
CLK4 Q9HAZ1 2/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
NEK2 P51955 1/20 0.33
DYRK1A Q13627 1/20 0.33
RPS6KA3 P51812 2/20 0.33
GAA P10253 2/20 0.32
KMT2A Q03164 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21548 1.00 CYP3A4 (0.40) CYP3A4TDP1ALDH1A1TP53MAPK1
SCHEMBL3220425 0.98 CYP3A4 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
Benzidine SCHEMBL4523874 0.98 CYP3A4 (0.41) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL526312 0.98 TDP1 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL1074845 0.98 TDP1 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrogen Peroxide SCHEMBL623863 0.96 RXRA (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Methyl Alcohol SCHEMBL27789369 0.96 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
SCHEMBL28406929 0.96 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL9474755 0.96 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Alcohol SCHEMBL27849531 0.93 RXRA (0.36) CYP3A4TDP1ALDH1A1TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114927009-A Aviation flight dangerous weather diagnosis and analysis system 国家气象中心(中央气象台) 2022-08-19 CN disclosed
CN-105753984-A Enzyme-linked immunity detection kit and application of early screening of solid tumors or cancers 美国爱普德诊断技术有限公司 2016-07-13 CN disclosed
CN-101084881-B Targeted quick-releasing effervescence preparation and preparation method thereof HUAIBEI HUIKE PHARMACEUTICAL CO LTD 2012-08-29 CN disclosed
CN-101084881-A Targeted quick-releasing effervescence preparation and preparation method thereof HUAIBEI HUIKE PHARMACEUTICAL C (CN) 2007-12-12 CN disclosed