Benzidine

Benzidine

SCHEMBL4523874

Cc1c(-c2ccc(N)cc2)ccc(N(C)C)c1C.Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 3/20 0.41
MAPK1 P28482 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35
DHFR P00374 1/20 0.34
ACHE P22303 2/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
CHEK1 O14757 1/20 0.32
NEK2 P51955 1/20 0.32
LIMK1 P53667 1/20 0.32
DYRK1A Q13627 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
RPS6KA3 P51812 1/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27687136 0.98 CYP3A4 (0.40) CYP3A4TDP1ALDH1A1TP53MAPK1
SCHEMBL21548 0.98 CYP3A4 (0.40) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL1074845 0.96 TDP1 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
SCHEMBL3220425 0.96 CYP3A4 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL526312 0.96 TDP1 (0.39) CYP3A4TDP1ALDH1A1TP53MAPK1
SCHEMBL28406929 0.95 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Methyl Alcohol SCHEMBL27789369 0.95 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrogen Peroxide SCHEMBL623863 0.95 RXRA (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Hydrochloric Acid SCHEMBL9474755 0.95 CYP3A4 (0.38) CYP3A4TDP1ALDH1A1TP53MAPK1
Alcohol SCHEMBL27849531 0.91 RXRA (0.36) CYP3A4TDP1ALDH1A1TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9395366-B2 Non-heating detection method for dermatophyte NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF FUKUI (JP) 2016-07-19 US disclosed
US-20150132777-A1 NON-HEATING DETECTION METHOD FOR DERMATOPHYTE MARUHO CO., LTD. (JP) 2015-05-14 US disclosed
US-8962264-B2 Non-heating detection method for dermatophyte NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF FUKUI (JP) 2015-02-24 US disclosed
EP-2009111-B1 NON-HEATING DETECTION METHOD FOR DERMATOPHYTE NAT UNIVERSITY CORP UNIVERSITY OF FUKUI (JP) 2013-05-29 EP disclosed
CN-101703404-B Method for showing fingerprints on various object surfaces and keeping DNA information UNIV NORTHEAST NORMAL 2012-01-11 CN disclosed
CN-102308002-A Novel diagnostic marker for type 1 diabetes mellitus SEOUL NAT UNIV HOSPITAL 2012-01-04 CN disclosed
CN-101703404-A Method for showing fingerprints on various object surfaces and keeping DNA information UNIV NORTHEAST NORMAL 2010-05-12 CN disclosed
US-20090226943-A1 Non-Heating Detection Method for Dermatophyte MARUHO CO., LTD. (JP) 2009-09-10 US disclosed
EP-2009111-A1 NON-HEATING DETECTION METHOD FOR DERMATOPHYTE National University Corporation University of Fukui (JP) 2008-12-31 EP disclosed