Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273539 | 0.87 | MAPT (0.60) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL17258266 | 0.82 | FABP4 (0.57) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL14675660 | 0.81 | FABP4 (0.56) | FABP3FABP4FABP5MAPTTDP1 | |
| Benzene SCHEMBL27688092 | 0.80 | MAPT (0.70) | MAPTTDP1CDC25BKDM4EALDH1A1 | |
| SCHEMBL10442502 | 0.80 | MAPT (0.56) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL16109256 | 0.80 | PDE4B (0.53) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL8186901 | 0.80 | CYP1A2 (0.51) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL5845535 | 0.79 | FABP4 (0.70) | FABP3FABP4FABP5TDP1CDC25B | |
| SCHEMBL7423032 | 0.79 | PDE4B (0.58) | FABP3FABP4FABP5MAPTTDP1 | |
| SCHEMBL2510102 | 0.79 | FABP4 (0.54) | FABP3FABP4FABP5MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1938323-A | Silinane compounds as cysteine protease inhibitors | SCHERING AG (DE) | 2007-03-28 | — | — | CN | claimed |
| CN-1938323-A | Silinane compounds as cysteine protease inhibitors | SCHERING AG (DE) | 2007-03-28 | — | — | CN | disclosed |