SCHEMBL2510102

SCHEMBL2510102

COc1ccc(C(=O)O)c(-c2ccccc2)c1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 3/20 0.54
▸ FABP3 P05413 3/20 0.54
▸ FABP5 Q01469 1/20 0.54
▸ ALDH1A1 P00352 2/20 0.50
▸ CDC25B P30305 2/20 0.48
▸ KDM4E B2RXH2 3/20 0.46
▸ MAPT P10636 2/20 0.46
▸ HPGD P15428 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ APAF1 O14727 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ CASP6 P55212 1/20 0.44
▸ CACNA1B Q00975 1/20 0.44
▸ APBA1 Q02410 1/20 0.44
▸ MCL1 Q07820 1/20 0.44
▸ CASP8 Q14790 1/20 0.44
▸ ALOX15 P16050 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17258266 0.87 FABP4 (0.57) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL7273539 0.82 MAPT (0.60) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL10442502 0.82 MAPT (0.56) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL1203086 0.79 ALDH1A1 (0.59) ALDH1A1CDC25BKDM4EMAPTHPGD
SCHEMBL27687571 0.79 FABP3 (0.58) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL11307508 0.78 EP300 (0.46) FABP4FABP3FABP5ALDH1A1KDM4E
SCHEMBL5845535 0.78 FABP4 (0.70) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL28261894 0.78 ESR1 (0.47) FABP4FABP3FABP5ALDH1A1CDC25B
SCHEMBL7170410 0.78 PTPN11 (0.56) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL3884497 0.78 KMT2A (0.47) FABP4ALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023019217-A1 DRY LIPOSOME ADJUVANT-CONTAINING VACCINES AND RELATED METHODS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-02-16 — — WO claimed
EP-4384215-A1 DRY POWDER COMPOSITIONS OF OIL-IN-WATER (O/W) EMULSION ADJUVANTED VACCINES Board of Regents, The University of Texas System (US) 2024-06-19 — — EP disclosed
WO-2023019194-A9 DRY POWDER COMPOSITIONS OF OIL-IN-WATER (O/W) EMULSION ADJUVANTED VACCINES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-09-14 — — WO disclosed
WO-2023019194-A1 DRY POWDER COMPOSITIONS OF OIL-IN-WATER (O/W) EMULSION ADJUVANTED VACCINES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-02-16 — — WO disclosed
WO-2023019217-A1 DRY LIPOSOME ADJUVANT-CONTAINING VACCINES AND RELATED METHODS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-02-16 — — WO disclosed
EP-2376522-A2 LOW VISCOSITY HIGHLY CONCENTRATED SUSPENSIONS Board of Regents, The University of Texas System (US) 2011-10-19 — — EP disclosed
WO-2010056657-A2 LOW VISCOSITY HIGHLY CONCENTRATED SUSPENSIONS BOARD OF REGENTS, THE UNIVESITY OF TEXAS SYSTEM (US) 2010-05-20 — — WO disclosed
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