Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 6/20 | 0.71 |
| ▸ | VKORC1 | Q9BQB6 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1649906 | 0.93 | NQO1 (0.75) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1647982 | 0.85 | NQO1 (0.71) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1648171 | 0.85 | NQO1 (0.79) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1648186 | 0.84 | NQO1 (1.00) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL29655586 | 0.82 | NQO1 (0.79) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1649892 | 0.82 | NQO1 (0.79) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL27687956 | 0.82 | NQO1 (0.60) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1649087 | 0.82 | NQO1 (0.67) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL1648127 | 0.82 | NQO1 (0.83) | NQO1VKORC1ALDH1A1MEN1ABCB11 | |
| SCHEMBL3177583 | 0.81 | VKORC1 (0.69) | NQO1VKORC1ALDH1A1MEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950353-B | Materials and methods for treating coagulation disorders | ARYX THERAPEUTICS | 2011-06-01 | — | — | CN | disclosed |
| CN-1950353-A | Materials and methods for treating coagulation disorders | ARYX THERAPEUTICS (US) | 2007-04-18 | — | — | CN | disclosed |