SCHEMBL1649892

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29655586	1.00	NQO1 (0.79)	NQO1VKORC1MEN1KMT2AALDH1A1
	Benzoic Acid SCHEMBL27687937	0.94	NQO1 (0.73)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1648186	0.89	NQO1 (1.00)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL13498415	0.88	NQO1 (0.72)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1649888	0.88	NQO1 (0.78)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1648171	0.86	NQO1 (0.79)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1648127	0.86	NQO1 (0.83)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL4958234	0.86	NQO1 (0.73)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1648030	0.85	NQO1 (0.68)	NQO1VKORC1MEN1KMT2AALDH1A1
	SCHEMBL1648184	0.85	VKORC1 (0.72)	NQO1VKORC1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.