Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 6/20 | 0.79 |
| ▸ | VKORC1 | Q9BQB6 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.68 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648186 | 0.89 | NQO1 (1.00) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10638322 | 0.87 | NQO1 (0.73) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1649906 | 0.87 | NQO1 (0.75) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL29655586 | 0.86 | NQO1 (0.79) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1649892 | 0.86 | NQO1 (0.79) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1648127 | 0.86 | NQO1 (0.83) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL27687938 | 0.85 | NQO1 (0.71) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL3175636 | 0.85 | NQO1 (0.81) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1648120 | 0.84 | VKORC1 (0.70) | NQO1VKORC1MEN1KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL27687937 | 0.83 | NQO1 (0.73) | NQO1VKORC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161261-B1 | Materials and methods for treating coagulation disorders | ARMETHEON INC (US) | 2013-08-28 | — | — | EP | disclosed |
| US-7932405-B2 | Halogenated ester derivatives of coumarins for the treatment of coagulation disorders | ARYX THERAPEUTICS, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| EP-2161261-A1 | Materials and methods for treating coagulation disorders | Aryx Therapeutics (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1735296-B1 | MATERIALS AND METHODS FOR TREATING COAGULATION DISORDERS | ARYX THERAPEUTICS (US) | 2009-12-09 | — | — | EP | disclosed |
| US-20090082430-A1 | Materials and Methods for Treating Coagulation Disorders | ARYX THERAPEUTICS, INC. (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082430-A1 | Materials and Methods for Treating Coagulation Disorders | F12, F2, SERPINC1 | NQO1 390/4885VKORC1 38/4885MEN1 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.