Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20029050 | 0.99 | EPHX2 (0.62) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL24414987 | 0.91 | HPGD (0.61) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL9876468 | 0.89 | POLB (0.48) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL18743946 | 0.89 | HPGD (0.58) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL17589268 | 0.88 | HPGD (0.52) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11957306 | 0.88 | HPGD (0.59) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL28270211 | 0.88 | EPHX2 (0.61) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL10030727 | 0.87 | MEN1 (0.57) | EPHX2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL7301925 | 0.86 | MMP2 (0.52) | EPHX2MEN1KMT2AALDH1A1HDAC3 | |
| SCHEMBL22271589 | 0.86 | EPHX2 (0.63) | EPHX2HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101120006-A | Proteasome inhibitors and methods of using the same | CEPHALON INC (US) | 2008-02-06 | — | — | CN | disclosed |