Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876521 | 0.97 | HDAC3 (0.49) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27688463 | 0.89 | EPHX2 (0.59) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL20029050 | 0.88 | EPHX2 (0.62) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7301925 | 0.86 | MMP2 (0.52) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL25448099 | 0.86 | MEN1 (0.51) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2006017 | 0.85 | ALDH1A1 (0.59) | POLBHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7303574 | 0.85 | LTA4H (0.52) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL17767806 | 0.85 | EPHX2 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17767811 | 0.85 | EPHX2 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL16167603 | 0.84 | ALDH1A1 (0.58) | HTTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043340-A | Antibody-drug conjugates; antitumor agents; leukemia; cancer | ELI LILLY AND COMPANY (US) | 1991-08-27 | — | — | US | disclosed |