Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708391 | 0.80 | TLR7 (0.69) | LMNATLR7POLBHRH2ADRA1D | |
| SCHEMBL29379266 | 0.79 | TLR7 (0.59) | LMNATLR7POLBHRH2ADRA1D | |
| SCHEMBL564029 | 0.79 | TLR7 (0.59) | LMNATLR7POLBHRH2ADRA1D | |
| Ammonia Solution, Strong SCHEMBL4818558 | 0.78 | TLR7 (0.58) | LMNATLR7POLBHRH2ADRA1D | |
| Hydrochloric Acid SCHEMBL5435065 | 0.78 | TLR7 (0.58) | LMNATLR7POLBHRH2ADRA1D | |
| SCHEMBL27708298 | 0.77 | TSHR (0.54) | LMNATLR7POLBHRH2ADRA1D | |
| Hydrochloric Acid SCHEMBL9602331 | 0.77 | TLR7 (0.56) | LMNATLR7POLBHRH2ADRA1D | |
| SCHEMBL30930028 | 0.75 | CYP1A2 (0.42) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29265624 | 0.75 | CYP1A2 (0.42) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2029970 | 0.75 | PDE4A (0.47) | LMNATLR7POLBPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014596-A | Imidazoquinolinylsulfonamides, imidazopyridinylsulfonamides, and imidazo-1, 5-naphthyridinylsulfonamides | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-08 | — | — | CN | disclosed |