Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HRH2 | P25021 | 1/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imiquimod SCHEMBL570774 | 0.82 | TLR7 (1.00) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL29357252 | 0.82 | TLR7 (1.00) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL26136 | 0.82 | TLR7 (1.00) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL1301796 | 0.81 | TLR7 (0.97) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL17962753 | 0.81 | TLR7 (0.97) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13248614 | 0.80 | TLR7 (0.70) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL27688679 | 0.80 | LMNA (0.42) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL5262205 | 0.79 | TLR7 (0.88) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3869660 | 0.79 | TLR7 (0.67) | TLR7LMNAPOLBHRH2ADRA1D | |
| Imiquimod SCHEMBL29029396 | 0.79 | TLR7 (0.93) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014596-A | Imidazoquinolinylsulfonamides, imidazopyridinylsulfonamides, and imidazo-1, 5-naphthyridinylsulfonamides | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-08 | — | — | CN | disclosed |