Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28041591 | 0.94 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19128 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL122091 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10995950 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL419170 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2353567 | 0.88 | — | — | |
| Bicarbonate SCHEMBL3359228 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL290407 | 0.88 | — | — | |
| Bicarbonate SCHEMBL7021729 | 0.88 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL20597717 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116654963-A | High alpha-Al 2 O 3 Preparation method of aluminum hydroxide with content and high alpha-Al thereof 2 O 3 Aluminum hydroxide in content and use | 山东大学 | 2023-08-29 | — | — | CN | claimed |
| CN-115090122-B | Ceramic membrane with alumina whisker membrane layer structure and preparation method and application thereof | 山东科技大学 | 2023-06-16 | — | — | CN | claimed |
| CN-110981529-A | Porous ceramic membrane material and preparation method and application thereof | 山东科技大学 | 2020-04-10 | — | — | CN | claimed |
| CN-105344356-B | A kind of alumina load Co catalysts and preparation method and the application in F- T synthesis | 中科潞安能源技术有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-105618052-B | A kind of porous aluminium oxide loaded cobalt fischer-tropsch synthetic catalyst and preparation method and application | 中科潞安能源技术有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-105618052-A | Fischer-Tropsch synthesizing catalyst prepared by carrying cobalt with porous aluminum oxide, preparation method and application | SHANXI INST COAL CHEMISTRY CAS | 2016-06-01 | — | — | CN | claimed |
| CN-105344356-A | Alumina loaded cobalt catalyst and preparation method and uses in Fischer-Tropsch synthesis | SHANXI COAL CHEM INST | 2016-02-24 | — | — | CN | claimed |
| CN-100584755-C | With kaolin is the method for feedstock production superfine white carbon black and nano aluminium oxide | CHINA KAOLIN CORP | 2010-01-27 | — | — | CN | claimed |
| CN-100457684-C | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2009-02-04 | — | — | CN | claimed |
| CN-101249965-A | Method for preparing ultra-fine white carbon black and nano alumina by using kaolinite as raw material | CHINA KAOLIN CORP (CN) | 2008-08-27 | — | — | CN | claimed |
| CN-101113095-A | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2008-01-30 | — | — | CN | claimed |
| CN-116654963-A | High alpha-Al 2 O 3 Preparation method of aluminum hydroxide with content and high alpha-Al thereof 2 O 3 Aluminum hydroxide in content and use | 山东大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-115090122-B | Ceramic membrane with alumina whisker membrane layer structure and preparation method and application thereof | 山东科技大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-115090122-A | Ceramic membrane with alumina whisker film layer structure and preparation method and application thereof | 山东科技大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-111470524-A | Preparation process of large-grain high-purity alumina | 苏州贝尔德新材料科技有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-100457684-C | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2009-02-04 | — | — | CN | disclosed |
| CN-100457684-C | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2009-02-04 | — | — | CN | disclosed |
| CN-101249965-A | Method for preparing ultra-fine white carbon black and nano alumina by using kaolinite as raw material | CHINA KAOLIN CORP (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101113095-A | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2008-01-30 | — | — | CN | disclosed |
| CN-101113095-A | Synthetic preparation method of A1N ceramic powder | UNIV HEBEI POLYTECHNIC (CN) | 2008-01-30 | — | — | CN | disclosed |