Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL15283203 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL301926 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17685557 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3359228 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL20597717 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7021729 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL950160 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6946373 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL18335331 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7112030 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 12408 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094704-A | Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material | — | 2026-05-26 | — | — | CN | claimed |
| CN-224283907-U | Steam pipeline heat insulation elbow | DEYANG DIXINJIA VALVE MANUFACTURE Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122067968-A | Al/N synergistic coating modified silicon-based composite anode material and preparation method and application thereof | 郑州大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037931-A | Gallium aluminate near-infrared luminescent material, preparation method thereof and near-infrared LED luminescent device | 重庆邮电大学 | 2026-05-15 | — | — | CN | claimed |
| EP-3890471-B1 | BIODEGRADABLE FOAM SUBSTRATE FOR GROWING PLANTS, PLANT SYSTEM PROVIDED THEREWITH, AND METHOD FOR MANUFACTURING SUCH SUBSTRATE | FOAMPLANT B V (NL) | 2026-05-06 | — | — | EP | claimed |
| US-12605333-B2 | Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release | TRIS PHARMA, INC. (US) | 2026-04-21 | — | — | US | claimed |
| US-20260096986-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A FLOATING INTERPENETRATING POLYMER NETWORK FORMING SYSTEM | TRIS PHARMA INC (US) | 2026-04-09 | — | — | US | claimed |
| US-12570582-B2 | Controlling carbonation | CARBONAIDE OY (FI) | 2026-03-10 | — | — | US | claimed |
| EP-3898818-B1 | METHOD OF PREPARING PHOSPHORUS-CONTAINING FLAME RETARDANTS AND THEIR USE IN POLYMER COMPOSITIONS | LANXESS CORP (US) | 2026-02-25 | — | — | EP | claimed |
| US-12559936-B2 | Flame retardant clear coatings for building panels | AWI LICENSING LLC (US) | 2026-02-24 | — | — | US | claimed |
| US-4511666-A | Process for producing beta'-silicon aluminum oxynitride (B'-SiAlON) | ALUMINUM COMPANY OF AMERICA (US) | 1985-04-16 | — | — | US | claimed |
| US-4500444-A | REACTING SODIUM ALUMINATE AND CARBON DIOXIDE AT PH ON ACID SIDE | BEEKMAN STEWART M (US) | 1985-02-19 | — | — | US | claimed |
| US-4499193-A | Process for producing beta'-silicon aluminum oxynitride (B'-SiAlON) using discrete particles | ALUMINUM COMPANY OF AMERICA (US) | 1985-02-12 | — | — | US | claimed |
| US-4465667-A | HYDROGENATED, HYDROLYZED GLUCOSE POLYMER, ALUMINUM HYDROXIDE | AKTIEBOLAGET HASSLE (SE) | 1984-08-14 | — | — | US | claimed |
| US-4416790-A | MIXING LIQUID PHASE WITH SOLIDS, WETTING AGENTS, ANTIOXIDANTS, VISCOSITY STABILIZERS, AND ALLOWING TO SWELL | SCHIEDEL GMBH & CO. (DE) | 1983-11-22 | — | — | US | claimed |
| EP-0092778-A1 | Process for preparing basic aluminum carbonate gels substantially free from foreign anions and fibrous colloidal alumina monohydrate of a boehmite crystal lattice structure | Beekman, Stewart M. (US) | 1983-11-02 | — | — | EP | claimed |
| US-4250168-A | Cold sore treatment method | CRAWFORD HORACE R | 1981-02-10 | — | — | US | claimed |
| US-4242140-A | SODIUM CARBONATE, ZINC SULFATE | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1980-12-30 | — | — | US | claimed |
| US-4216337-A | FROM POLYCARBOXYLIC ACIDS AND ALCOHOLS FOR USE AS PLASTICIZERS, HEAT TREATMENT THEN ADSORPTION PURIFIES THE PRODUCT | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1980-08-05 | — | — | US | claimed |
| US-4126561-A | ADHESIVE, WATER-INSOLUBLE PARTICLES, AND ADDTIVIES TO IMPART PROPERTIES | GRANUM INCORPORATED | 1978-11-21 | — | — | US | claimed |