Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4929399 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19128 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL97148 | 0.94 | — | — | |
| Bicarbonate SCHEMBL7021729 | 0.88 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL16143300 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL225293 | 0.88 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15283203 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2947807 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL301926 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6946373 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116533348-A | Artificial wood product and method for producing the same | 3RT控股私人有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-107848140-B | Artificial wood product and method for producing the same | 3RT控股私人有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-116533348-A | Artificial wood product and method for producing the same | 3RT控股私人有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-107848140-B | Artificial wood product and method for producing the same | 3RT控股私人有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-8668447-B2 | Steam turbine blade and method for manufacturing the same | KABUSHIKI KAISHA TOSHIBA (JP) | 2014-03-11 | — | — | US | disclosed |
| WO-2012158538-A2 | FASTENER SYSTEM WITH VARIOUS ADHESIVES | AVERY DENNISON CORPORATION (US) | 2012-11-22 | — | — | WO | disclosed |
| US-20100166548-A1 | STEAM TURBINE BLADE AND METHOD FOR MANUFACTURING THE SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-07-01 | — | — | US | disclosed |
| US-5405678-A | Base with coating of hydrophobic polymeric latex which is not fully coalesced and has an acid value less than three | OTIS SPECIALTY PAPERS INC. (US) | 1995-04-11 | — | — | US | disclosed |