Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746106 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTGFERSMN1; SMN2MEN1 | |
| SCHEMBL393596 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTGFERSMN1; SMN2HTR2B | |
| SCHEMBL2206444 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MAPTGFERSMN1; SMN2HTR2B | |
| SCHEMBL394896 | 0.76 | MAPT (1.00) | ALDH1A1MAPTGFERSMN1; SMN2HTR2B | |
| SCHEMBL2267850 | 0.76 | MAPT (0.67) | ALDH1A1MAPTMEN1KMT2ADRD2 | |
| SCHEMBL12824550 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTGFERSMN1; SMN2MEN1 | |
| SCHEMBL27812649 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTGFERSMN1; SMN2KMT2A | |
| SCHEMBL2207168 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AHTR2B | |
| Hydrochloric Acid SCHEMBL10848491 | 0.75 | MAPT (0.65) | ALDH1A1MAPTMEN1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL2206671 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85108623-A | Preparation has the novel method of the heterocycleamide of medical active | — | 1986-07-30 | — | — | CN | disclosed |