Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.48 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681265 | 0.85 | HRH4 (0.52) | HRH4ADRB2NCF1PLD1PRKD1 | |
| SCHEMBL30489430 | 0.85 | USP30 (0.47) | HRH4PRKD1PRKD2PRKD3THRB | |
| SCHEMBL31704842 | 0.82 | HRH4 (0.52) | HRH4ADRB2NCF1PLD1CHRNB2 | |
| SCHEMBL29960561 | 0.82 | HRH4 (0.52) | HRH4ADRB2NCF1PLD1HTR1A | |
| SCHEMBL29115424 | 0.82 | HRH4 (0.52) | HRH4ADRB2NCF1PLD1HTR1A | |
| SCHEMBL11355924 | 0.82 | HRH4 (0.52) | HRH4ADRB2NCF1PLD1CHRNB2 | |
| Hydrochloric Acid SCHEMBL900436 | 0.81 | HRH4 (0.51) | HRH4ADRB2NCF1PLD1HTR1A | |
| SCHEMBL15511394 | 0.81 | HRH4 (0.54) | HRH4PIM1PIM3HTT | |
| SCHEMBL4933955 | 0.78 | CHRNB2 (0.55) | CHRNB2CHRNA4PIM1PIM3ACVR1 | |
| SCHEMBL16432179 | 0.78 | ADRB1 (0.54) | PRKD1PRKD2PRKD3HTR1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87102873-A | Phenylpiperazine anti-dysrhythmia agents and preparation method thereof | — | 1987-10-28 | — | — | CN | disclosed |