SCHEMBL27692000

SCHEMBL27692000

Oc1ccc(-c2ccccc2)c(O)c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.50
ALOX5 P09917 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
BCL2L1 Q07817 1/20 0.48
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HNF4A P41235 1/20 0.42
PDE4B Q07343 2/20 0.41
PDE4A P27815 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
GYS1 P13807 1/20 0.40
ESR2 Q92731 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351964 1.00 BACE1 (0.50) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL28901480 0.85 BACE1 (0.48) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL1513817 0.84 BACE1 (0.52) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL2936729 0.83 HDAC4 (0.47) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL19824468 0.81 ALOX5 (0.48) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL27492972 0.81 BACE1 (0.48) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL27561397 0.80 ESR2 (0.48) ALDH1A1HPGDHSD17B10ESR2ALOX15
SCHEMBL30669867 0.79 BACE1 (0.56) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL79394 0.79 BACE1 (0.56) BACE1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL3976573 0.78 HDAC4 (0.61) BACE1ALOX5ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101080454-B Cellulose acylate film, method for producing cellulose acylate film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO LTD 2012-10-17 CN disclosed
CN-101080454-A Cellulose acylate film, method for producing cellulose acylate film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO LTD (JP) 2007-11-28 CN disclosed