Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269586 | 0.85 | SYK (0.62) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL19347495 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL2284267 | 0.82 | EGFR (0.72) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL31316191 | 0.81 | CNR1 (0.55) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL22347706 | 0.81 | CNR1 (0.55) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL1121223 | 0.80 | RAB9A (0.67) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL28762614 | 0.80 | SYK (0.67) | SYKPIK3CGMEN1KMT2ARAF1 | |
| SCHEMBL5706320 | 0.79 | SYK (0.53) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL13924556 | 0.79 | SYK (0.69) | SYKPIK3CGPIK3CAPIK3CBCDK5 | |
| SCHEMBL13605438 | 0.78 | PIK3CG (0.51) | SYKPIK3CGPIK3CAPIK3CBCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | claimed |
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | disclosed |