Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.59 |
| ▸ | SYK | P43405 | 2/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410879 | 0.86 | EGFR (0.60) | EGFRPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL1377802 | 0.84 | EGFR (1.00) | EGFRPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL91589 | 0.84 | EGFR (0.74) | EGFRPIK3CGPIK3CAPIK3CBMAPK1 | |
| SCHEMBL22191547 | 0.83 | SYK (0.60) | EGFRPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL1085867 | 0.82 | MEN1 (0.71) | EGFRMEN1KMT2AMAPK1MAPT | |
| SCHEMBL27692103 | 0.82 | SYK (0.69) | EGFRPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL30754730 | 0.82 | MEN1 (0.65) | EGFRPIK3CGPIK3CAPIK3CBMEN1 | |
| Hydrochloric Acid SCHEMBL12813301 | 0.82 | EGFR (0.71) | EGFRPIK3CGPIK3CAPIK3CBKCNH3 | |
| SCHEMBL7466253 | 0.82 | PIK3CG (0.71) | EGFRPIK3CGPIK3CAPIK3CBMAPK1 | |
| SCHEMBL7968715 | 0.81 | MEN1 (0.66) | EGFRMEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | EGFR 2324/4885PIK3CG 4241/4885PIK3CA 3293/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | EGFR 2165/4885PIK3CG 4256/4885PIK3CA 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.