Agmatine

Agmatine

SCHEMBL27692425

N=C(N)NCCCCN.NC(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 2/20 0.54
ALOX15 P16050 2/20 0.48
CYP1A2 P05177 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
CA12 O43570 1/20 0.39
F13A1 P00488 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
TSHR P16473 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Agmatine SCHEMBL29233378 0.93 PAOX (0.52) PAOXALOX15CYP1A2SMN1; SMN2MEN1
Agmatine SCHEMBL19647 0.93
Agmatine SCHEMBL8579204 0.93 CYP1A2 (0.54) PAOXALOX15CYP1A2SMN1; SMN2MEN1
Agmatine SCHEMBL30819275 0.93
Agmatine SCHEMBL5665180 0.93 CYP1A2 (0.54) PAOXALOX15CYP1A2SMN1; SMN2MEN1
Agmatine SCHEMBL23364117 0.91 CYP1A2 (0.52) PAOXALOX15CYP1A2SMN1; SMN2MEN1
Agmatine SCHEMBL7391507 0.91 SMN1; SMN2 (0.52) PAOXALOX15CYP1A2SMN1; SMN2MEN1
SCHEMBL5670730 0.91 CYP1A2 (0.57) PAOXALOX15CYP1A2SMN1; SMN2MEN1
SCHEMBL433609 0.91 CYP1A2 (0.57) PAOXALOX15CYP1A2SMN1; SMN2MEN1
Agmatine SCHEMBL20636599 0.91 SMN1; SMN2 (0.52) PAOXALOX15CYP1A2SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101010433-A Biochemical synthesis of 1, 4-butanediamine DSM IP ASSETS BV (NL) 2007-08-01 CN claimed
CN-101006183-A Biochemical synthesis of 1,4-butanediamine DSM IP ASSETS BV (NL) 2007-07-25 CN claimed
CN-101010433-B Biochemical synthesis of 1, 4-butanediamine DSM IP ASSETS BV 2012-03-07 CN disclosed
CN-101006183-B Biochemical synthesis of 1,4-butanediamine DSM IP ASSETS BV 2011-07-27 CN disclosed
CN-101010433-A Biochemical synthesis of 1, 4-butanediamine DSM IP ASSETS BV (NL) 2007-08-01 CN disclosed
CN-101006183-A Biochemical synthesis of 1,4-butanediamine DSM IP ASSETS BV (NL) 2007-07-25 CN disclosed