Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693228 | 0.92 | CXCR2 (0.46) | CXCR2RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL27712958 | 0.92 | CXCR2 (0.57) | CXCR2RAB9AMAPTL3MBTL1CNR2 | |
| SCHEMBL27713046 | 0.89 | CXCR2 (0.57) | CXCR2MAPTSMN1; SMN2ALDH1A1MAOB | |
| SCHEMBL27693224 | 0.89 | CXCR2 (0.45) | CXCR2RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL27693429 | 0.88 | CXCR2 (0.49) | CXCR2MAPTNPC1 | |
| SCHEMBL27693236 | 0.87 | CXCR2 (0.53) | CXCR2RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL27713037 | 0.85 | CXCR2 (0.44) | CXCR2RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL27693207 | 0.85 | ALOX5AP (0.47) | CXCR2 | |
| SCHEMBL485769 | 0.85 | CXCR2 (0.68) | CXCR2FAAHCNR2CNR1ALDH1A1 | |
| SCHEMBL28770785 | 0.85 | CXCR2 (0.42) | CXCR2MAPTSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | claimed |
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | disclosed |