Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27712959 | 0.92 | CNR2 (0.56) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27693230 | 0.92 | DRD4 (0.52) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27713047 | 0.89 | CXCR2 (0.58) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27693432 | 0.88 | CXCR2 (0.46) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27693239 | 0.87 | CXCR2 (0.47) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27712967 | 0.85 | KMT2A (0.55) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27713038 | 0.85 | PIN1 (0.42) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| Formic Acid SCHEMBL27693208 | 0.85 | ALOX5AP (0.51) | KMT2AALDH1A1CNR2CNR1RAB9A | |
| Formic Acid SCHEMBL28770786 | 0.84 | CHRM1 (0.46) | MEN1KMT2AALDH1A1SGMS2CNR2 | |
| SCHEMBL485699 | 0.84 | CXCR2 (0.62) | MEN1KMT2AALDH1A1SGMS2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | claimed |
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | disclosed |