Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2769608 | 0.99 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CAHRCDK4 | |
| SCHEMBL2771388 | 0.84 | AOC3 (0.49) | CYP2C9CYP2C19MAOB | |
| Hydrochloric Acid SCHEMBL2768923 | 0.83 | AOC3 (0.51) | CYP2C9CYP2C19MAOB | |
| Hydrochloric Acid SCHEMBL2769962 | 0.77 | INPPL1 (0.43) | KMT2ACYP1A2CYP3A4CYP2C19SLC26A4 | |
| SCHEMBL2769084 | 0.76 | MEN1 (0.41) | ACHEKMT2ACYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL2770459 | 0.75 | HTT (0.40) | ACHEKMT2AMAOBMPORAB9A | |
| SCHEMBL5810951 | 0.75 | CYP1A2 (0.48) | ADRA2AADRA2BADRA2CAHRCDK4 | |
| SCHEMBL5810790 | 0.69 | CYP1A2 (0.42) | ADRA2AADRA2BADRA2CAHRACHE | |
| SCHEMBL3521430 | 0.68 | CDK4 (0.60) | ADRA2AADRA2BADRA2CCDK4CCND1 | |
| Bromide SCHEMBL27650271 | 0.66 | CDK4 (0.58) | ADRA2AADRA2BADRA2CCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805177-B9 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-09-15 | — | — | EP | claimed |
| EP-1805177-B1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-04-28 | — | — | EP | claimed |
| EP-1805177-A4 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-07-29 | — | — | EP | disclosed |
| EP-1805177-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006025715-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |