Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19340026 | 0.87 | BRD4 (0.54) | ESR1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL29663000 | 0.82 | KMT2A (0.63) | NR1H3KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL14600350 | 0.82 | KMT2A (0.63) | NR1H3KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL23074284 | 0.81 | BRD4 (0.51) | ESR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL29382180 | 0.81 | KMT2A (0.53) | ESR1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL15295071 | 0.81 | KMT2A (0.53) | ESR1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5866595 | 0.80 | ALDH1A1 (0.58) | ESR1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL30231754 | 0.77 | CA9 (0.69) | ESR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL8604716 | 0.77 | CA9 (0.69) | ESR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL13780757 | 0.77 | CA9 (0.67) | KMT2AMEN1ALDH1A1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133513-B2 | Solid preparation having improved solubility | SHIONOGI & CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133513-B2 | Solid preparation having improved solubility | SHIONOGI & CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20100240711-A1 | SOLID PREPARATION COMPRISING NPYY5 RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20090105312-A1 | SOLID PREPARATION HAVING IMPROVED SOLUBILITY | SHIONOGI & CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| US-20090105312-A1 | SOLID PREPARATION HAVING IMPROVED SOLUBILITY | SHIONOGI & CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105312-A1 | SOLID PREPARATION HAVING IMPROVED SOLUBILITY | NUDT1, PDE7A, SLC7A1 | ESR1 4339/4885NR1H3 2748/4885KMT2A 2635/4885 |
| US-20100240711-A1 | SOLID PREPARATION COMPRISING NPYY5 RECEPTOR ANTAGONIST | NPY5R, SSTR5, NPY1R | ESR1 942/4885NR1H3 1381/4885KMT2A 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.