Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740561 | 0.80 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL4865776 | 0.76 | PTPN5 (0.53) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| Acetaldehyde SCHEMBL27715843 | 0.74 | PTPN1 (0.44) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| SCHEMBL3738707 | 0.71 | PTPN1 (0.50) | PTPN1PTPN2PGK1PGK2 | |
| SCHEMBL3742005 | 0.70 | ALDH1A1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL27715840 | 0.69 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL3736650 | 0.69 | PTPN1 (0.48) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| SCHEMBL7598901 | 0.68 | PTPN1 (0.47) | PTPN1PTPN2 | |
| SCHEMBL27695973 | 0.68 | PTPN1 (0.45) | PTPN1PTPN2PGK1PGK2 | |
| SCHEMBL4100154 | 0.67 | PTPN1 (0.41) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094677-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR INC (US) | 2007-12-26 | — | — | CN | disclosed |