Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001887 | 0.76 | PTPN1 (0.50) | PTPN1PTPN2PTPRC | |
| SCHEMBL4865776 | 0.71 | PTPN5 (0.53) | PTPN1PTPN2 | |
| SCHEMBL27695973 | 0.70 | PTPN1 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL3738707 | 0.69 | PTPN1 (0.50) | PTPN1PTPN2PTPRC | |
| SCHEMBL3736650 | 0.69 | PTPN1 (0.48) | PTPN1PTPN2 | |
| SCHEMBL3740561 | 0.69 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL19480545 | 0.68 | PTPN1 (0.51) | PTPN1PTPN2PTPRC | |
| SCHEMBL3729935 | 0.68 | PTPN1 (0.51) | PTPN1PTPN2PTPRC | |
| SCHEMBL3742005 | 0.67 | ALDH1A1 (0.55) | PTPN1PTPN2 | |
| Methane SCHEMBL27696014 | 0.67 | PTPN1 (0.40) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2009-05-21 | — | — | US | claimed |
| US-20060142250-A1 | Protein tyrosine phosphatase inhibitors and methods of use thereof | FALCON TECHNOLOGY PARTNERS L.P. | 2006-06-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142250-A1 | Protein tyrosine phosphatase inhibitors and methods of use thereof | PPM1B, PTPN1, PTPN5 | PTPN1 2/4885PTPN2 5/4885PTPRC 21/4885 |
| US-20090131374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PPM1B, PTPN1, PTPN5 | PTPN1 2/4885PTPN2 5/4885PTPRC 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.