Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185564 | 0.80 | CFB (0.41) | HRH3RIPK1KCNH2 | |
| SCHEMBL29943144 | 0.80 | CHRNB2 (0.53) | AKR1C3AKR1C1RIPK1NOTUML3MBTL1 | |
| SCHEMBL4102035 | 0.79 | CHRNB2 (0.48) | HRH3RIPK1KCNH2 | |
| SCHEMBL22473211 | 0.78 | CHRNB2 (0.42) | HRH3RIPK1KCNH2 | |
| SCHEMBL25053382 | 0.77 | CFB (0.41) | HRH3RIPK1KCNH2 | |
| SCHEMBL580929 | 0.77 | AKR1C3 (0.51) | AKR1C3AKR1C1RIPK1NOTUML3MBTL1 | |
| SCHEMBL22473161 | 0.77 | CHRNB2 (0.41) | HRH3RIPK1KCNH2 | |
| SCHEMBL25053364 | 0.77 | CFB (0.41) | HRH3RIPK1KCNH2 | |
| SCHEMBL4558489 | 0.77 | TDP1 (0.46) | RIPK1 | |
| SCHEMBL27696098 | 0.77 | CHRNB2 (0.38) | HRH3RIPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100345853-C | Pyrazolopyrimidine compound and method for producing the same | TANABE SEIYAKU CO (JP) | 2007-10-31 | — | — | CN | disclosed |