Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741657 | 0.80 | PGK1 (0.53) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| SCHEMBL13850056 | 0.75 | PGK1 (0.44) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| SCHEMBL27715848 | 0.71 | PGK1 (0.41) | PTPN1PTPN2PGK1PGK2 | |
| SCHEMBL3738148 | 0.70 | PGK1 (0.53) | PTPN1PTPN5PGK1PGK2PTPRC | |
| SCHEMBL3737925 | 0.67 | PTPN1 (0.70) | PTPN1PTPN2PTPN5PGK1PGK2 | |
| SCHEMBL31156144 | 0.67 | AR (0.40) | AR | |
| SCHEMBL25239302 | 0.66 | PTPN1 (0.43) | PTPN1PTPN2PTPN5PTPRC | |
| SCHEMBL3872784 | 0.66 | TSHR (0.38) | AR | |
| SCHEMBL3745971 | 0.66 | PTPRC (0.54) | PTPN1PTPN2PGK1PGK2PTPRC | |
| SCHEMBL3732105 | 0.64 | PTPN1 (0.74) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094677-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR INC (US) | 2007-12-26 | — | — | CN | claimed |
| CN-101094677-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR INC (US) | 2007-12-26 | — | — | CN | disclosed |