Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3881594 | 0.98 | POLB (0.50) | POLBRAB9ASLC18A3SIGMAR1MKNK1 | |
| SCHEMBL6032677 | 0.86 | MKNK1 (0.60) | POLBMKNK1MKNK2MEN1KMT2A | |
| SCHEMBL1108507 | 0.85 | RAB9A (0.53) | POLBRAB9AHPGDSKMT2AKDM4E | |
| SCHEMBL20134937 | 0.84 | SMN1; SMN2 (0.49) | RAB9AMKNK1MKNK2MEN1KMT2A | |
| SCHEMBL2755249 | 0.84 | MKNK1 (0.49) | POLBRAB9AMKNK1MKNK2MEN1 | |
| Bromide SCHEMBL1940375 | 0.84 | MKNK1 (0.58) | POLBMKNK1MKNK2MEN1KMT2A | |
| SCHEMBL31601766 | 0.84 | MKNK1 (0.47) | POLBRAB9AMKNK1MKNK2MEN1 | |
| SCHEMBL31601661 | 0.84 | ALDH1A1 (0.51) | MKNK1MKNK2HPGDSALDH1A1HSD17B10 | |
| SCHEMBL31601884 | 0.84 | ALDH1A1 (0.51) | MKNK1MKNK2HPGDSALDH1A1HSD17B10 | |
| SCHEMBL31601724 | 0.81 | HTR2C (0.53) | POLBMKNK1MKNK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058674-A | 4 (1H-pyrazol-3-yl) piperidinyl derivative, preparation method thereof and application thereof in preparation of MNK inhibitor | 烟台新药创制山东省实验室 | 2025-05-30 | — | — | CN | disclosed |
| CN-101094854-A | Constrained compounds as cgrp-receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2007-12-26 | — | — | CN | disclosed |