Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25658173 | 0.90 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13674044 | 0.88 | CTSK (0.40) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28969069 | 0.86 | ATM (0.36) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14027734 | 0.86 | MEN1 (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28969072 | 0.86 | ATM (0.36) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL24629628 | 0.86 | CTSK (0.36) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14220437 | 0.86 | CYP2D6 (0.39) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL27939686 | 0.85 | CA2 (0.35) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL21480838 | 0.85 | CA2 (0.35) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14497007 | 0.84 | CA1 (0.35) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228182-A | Antibakterielle amid-makrozyklen v | AICURIS GMBH & CO KG (DE) | 2008-07-23 | — | — | CN | disclosed |
| CN-101090909-A | Antibacterial amide macrocycles IV | AICURIS GMBH & CO KG (DE) | 2007-12-19 | — | — | CN | disclosed |