SCHEMBL27697131

SCHEMBL27697131

O=C(ON1CCCC(c2nc3ccccc3s2)C1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2M P61081 13/20 0.48
DCUN1D1 Q96GG9 13/20 0.48
LMNA P02545 3/20 0.48
ALDH1A1 P00352 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
GFER P55789 1/20 0.48
TP53 P04637 2/20 0.48
NEDD4 P46934 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18996008 0.74 NEDD4 (0.62) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL27697132 0.74 UBE2M (0.51) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18657543 0.74 UBE2M (0.62) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18657452 0.74 UBE2M (0.62) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18657960 0.74 UBE2M (0.78) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL21392777 0.73 UBE2M (0.82) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18658188 0.73 UBE2M (0.78) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18657454 0.73 UBE2M (0.68) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL18657958 0.72 MAPT (0.69) UBE2MDCUN1D1LMNAALDH1A1CYP1A2
SCHEMBL2575610 0.71 UBE2M (0.47) UBE2MDCUN1D1LMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101014595-A Novel cyclic aminobenzoic acid derivative KYORIN SEIYAKU KK (JP) 2007-08-08 CN disclosed