Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.72 |
| ▸ | PRKCG | P05129 | 3/20 | 0.72 |
| ▸ | PRKCB | P05771 | 3/20 | 0.72 |
| ▸ | SRC | P12931 | 3/20 | 0.72 |
| ▸ | PRKCA | P17252 | 3/20 | 0.72 |
| ▸ | PRKCH | P24723 | 3/20 | 0.72 |
| ▸ | PRKCI | P41743 | 3/20 | 0.72 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.72 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.72 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.72 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369690 | 0.84 | EGFR (0.68) | EGFRKMT2APRKD3PRKCGPRKCB | |
| Cgp-53353 SCHEMBL29766901 | 0.84 | EGFR (1.00) | EGFRKMT2APRKD3PRKCGPRKCB | |
| Cgp-53353 SCHEMBL230492 | 0.84 | EGFR (1.00) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL9566653 | 0.82 | KMT2A (0.49) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL10600683 | 0.82 | PPOX (0.69) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL9566667 | 0.82 | APP (0.61) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL22032609 | 0.79 | MAPT (0.54) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL29535893 | 0.78 | GRM5 (0.63) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL1953630 | 0.78 | GRM5 (0.63) | EGFRKMT2APRKD3PRKCGPRKCB | |
| SCHEMBL10423465 | 0.77 | PPOX (0.47) | EGFRKMT2APRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110290800-A | Conjugating biomolecules, medical composition and method | 台湾浩鼎生技股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-107794302-A | Determine method of the cancer to EGF-R ELISA magnetic target therapy reactivity | 综合医院公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-102586431-A | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments | GEN HOSPITAL CORP | 2012-07-18 | — | — | CN | disclosed |
| CN-101501211-A | Method for Determining Responsiveness of Cancer to Epidermal Growth Factor Receptor Targeted Therapy | GEN HOSPITAL CORP (US) | 2009-08-05 | — | — | CN | disclosed |
| CN-101084015-A | Antibody formulations in histidine-acetate buffer | GENENTECH INC (US) | 2007-12-05 | — | — | CN | disclosed |