SCHEMBL9566653

SCHEMBL9566653

Nc1ccc(Nc2ccc3c(c2)C(=O)NC3=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
EGFR P00533 4/20 0.49
PRKD3 O94806 3/20 0.49
PRKCG P05129 3/20 0.49
PRKCB P05771 3/20 0.49
SRC P12931 3/20 0.49
PRKCA P17252 3/20 0.49
PRKCH P24723 3/20 0.49
PRKCI P41743 3/20 0.49
PRKCE Q02156 3/20 0.49
PRKCQ Q04759 3/20 0.49
PRKCZ Q05513 3/20 0.49
PRKCD Q05655 3/20 0.49
PRKD1 Q15139 3/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
ABL1 P00519 1/20 0.49
ABL2 P42684 1/20 0.49
PPOX P50336 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566671 0.85 ATM (0.55) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL8834514 0.84 EGFR (0.69) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL27369690 0.84 EGFR (0.68) KMT2AEGFRPRKD3PRKCGPRKCB
Diphenylamine SCHEMBL27637720 0.83 ALDH1A1 (0.62) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL10600683 0.82 PPOX (0.69) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL9566667 0.82 APP (0.61) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL27697134 0.82 EGFR (0.72) KMT2AEGFRPRKD3PRKCGPRKCB
SCHEMBL5637546 0.80 MAPT (0.59) KMT2AMEN1MAPTALDH1A1KDM4E
SCHEMBL29664158 0.79 MAPK14 (0.59) KMT2AMEN1MAPTTDP1MAPK14
SCHEMBL9566666 0.79 ATM (0.75) KMT2AEGFRSRCMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed