Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093694 | 0.93 | CRACR2A (0.47) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL27717245 | 0.89 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL27697212 | 0.89 | MAPT (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL27717099 | 0.84 | MEN1 (0.53) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL10187725 | 0.83 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2096498 | 0.83 | CRACR2A (0.47) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL13358991 | 0.81 | CRACR2A (0.45) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL13058248 | 0.81 | CRACR2A (0.45) | RAB9ANPC1ALDH1A1GRM4HTT | |
| SCHEMBL2090600 | 0.81 | RAB9A (0.45) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL27697218 | 0.81 | CRACR2A (0.52) | RAB9ANPC1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | claimed |
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | disclosed |