Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764187 | 0.93 | CRACR2A (0.53) | CRACR2AP4HTMLMNANPC1RAB9A | |
| SCHEMBL2091533 | 0.91 | CRACR2A (0.46) | CRACR2AP4HTMLMNADGAT1 | |
| SCHEMBL27717099 | 0.85 | MEN1 (0.53) | P4HTMLMNAMEN1KMT2ATDP1 | |
| SCHEMBL27697216 | 0.81 | RAB9A (0.47) | LMNAMEN1KMT2ATDP1NPC1 | |
| SCHEMBL27697212 | 0.80 | MAPT (0.53) | CRACR2ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL27717245 | 0.80 | RAB9A (0.54) | LMNAMEN1KMT2ATDP1NPC1 | |
| SCHEMBL2095544 | 0.80 | CRACR2A (0.54) | CRACR2ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL10187707 | 0.78 | MEN1 (0.44) | CRACR2ALMNAMEN1KMT2ATDP1 | |
| SCHEMBL2093501 | 0.78 | GSK3B (0.37) | CRACR2ALMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL2093588 | 0.78 | LMNA (0.43) | LMNAMEN1KMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | claimed |