Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25382278 | 0.77 | NOTUM (0.39) | ALDH1A1PTGS1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL7557950 | 0.76 | MEN1 (0.45) | ALDH1A1MEN1KMT2ACYP1A2HTT | |
| SCHEMBL17743745 | 0.76 | MEN1 (0.45) | ALDH1A1MEN1KMT2ACYP1A2HTT | |
| SCHEMBL2048930 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9402020 | 0.76 | KMT2A (0.45) | ALDH1A1MEN1KMT2ACYP1A2HTT | |
| SCHEMBL5390679 | 0.76 | MAPT (0.47) | ALDH1A1MEN1KMT2ACYP1A2HTT | |
| SCHEMBL3967152 | 0.75 | L3MBTL1 (0.50) | ALDH1A1KMT2ACYP1A2HTTSMN1; SMN2 | |
| SCHEMBL3750875 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP1A2HTT | |
| SCHEMBL3746738 | 0.73 | PDE4A (0.46) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9615636 | 0.73 | KMT2A (0.48) | ALDH1A1MEN1KMT2ACYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | disclosed |