Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | XPO1 | O14980 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806220 | 1.00 | NFE2L2 (0.43) | NFE2L2NR1H4ALDH1A1ESR1GAA | |
| SCHEMBL998917 | 0.84 | CA12 (0.42) | NR1H4ESR1P4HTMKMT2ALMNA | |
| SCHEMBL998915 | 0.84 | CA12 (0.42) | NR1H4ESR1P4HTMKMT2ALMNA | |
| SCHEMBL26698471 | 0.83 | STK17B (0.39) | NR1H4ALDH1A1ESR1XPO1KMT2A | |
| SCHEMBL3772958 | 0.83 | CA12 (0.56) | NFE2L2ALDH1A1ESR1GAAP4HTM | |
| SCHEMBL3772961 | 0.83 | CA12 (0.56) | NFE2L2ALDH1A1ESR1GAAP4HTM | |
| SCHEMBL7936748 | 0.82 | MET (0.47) | NR1H4ESR1P4HTMKMT2ALMNA | |
| SCHEMBL1768856 | 0.82 | MET (0.47) | NR1H4ESR1P4HTMKMT2ALMNA | |
| SCHEMBL15278590 | 0.82 | ESR1 (0.40) | NR1H4ESR1P4HTMKMT2ALMNA | |
| SCHEMBL7014079 | 0.81 | NPC1 (0.48) | ALDH1A1ESR1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014580-B | Morpholine compound | MITSUBISHI PHARMA CORP | 2011-05-04 | — | — | CN | disclosed |
| CN-101014580-A | Morpholine compound | MITSUBISHI PHARMA CORP (JP) | 2007-08-08 | — | — | CN | disclosed |