Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697440 | 0.94 | PPARG (0.45) | PPARGKDM4EUSP14MAPK8CYP1A2 | |
| SCHEMBL333958 | 0.92 | KDM4E (0.42) | PPARGKDM4EUSP14MAPK8CYP1A2 | |
| SCHEMBL27717567 | 0.86 | PPARG (0.41) | PPARGKDM4EUSP14CYP1A2CYP3A4 | |
| SCHEMBL333957 | 0.86 | MAPT (0.42) | PPARGKDM4EUSP14MAPK8CYP1A2 | |
| SCHEMBL333839 | 0.83 | PPARG (0.47) | PPARGKDM4EUSP14MEN1KMT2A | |
| SCHEMBL334342 | 0.83 | USP14 (0.45) | PPARGKDM4EUSP14MEN1KMT2A | |
| SCHEMBL27697434 | 0.81 | PTGER4 (0.44) | PPARGKDM4EUSP14SMN1; SMN2 | |
| SCHEMBL27717661 | 0.81 | MAPT (0.56) | PPARGKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28767827 | 0.77 | USP14 (0.43) | KDM4EUSP14MEN1KMT2AMAPT | |
| SCHEMBL334103 | 0.76 | PTGES (0.50) | USP14MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142185-A | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2008-03-12 | — | — | CN | disclosed |