SCHEMBL27697453

SCHEMBL27697453

O=C(Oc1cc(O)ccc1O)c1cccc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.73
GAA P10253 2/20 0.73
POLB P06746 1/20 0.73
EGFR P00533 1/20 0.53
GFER P55789 1/20 0.47
ESR1 P03372 5/20 0.46
ESR2 Q92731 4/20 0.46
MEN1 O00255 4/20 0.46
DEGS1 O15121 1/20 0.46
MAPT P10636 3/20 0.45
HTT P42858 2/20 0.45
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPK1 P28482 1/20 0.44
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 P62805 1/20 0.43
EP300 Q09472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27773732 0.84 KMT2A (1.00) KMT2AGAAPOLBEGFRESR1
SCHEMBL13683087 0.79 GAA (0.60) KMT2AGAAPOLBEGFRESR1
SCHEMBL8367791 0.79 KMT2A (0.78) KMT2AGAAPOLBESR1ESR2
SCHEMBL11754236 0.78 KMT2A (0.76) KMT2AGAAPOLBESR1ESR2
SCHEMBL27538218 0.77 GAA (0.57) KMT2AGAAPOLBESR1ESR2
SCHEMBL28898508 0.76 KMT2A (0.68) KMT2AGAAPOLBESR1ESR2
SCHEMBL29392731 0.75 KMT2A (0.77) KMT2AGAAPOLBEGFRESR1
SCHEMBL25135 0.75 KMT2A (0.77) KMT2AGAAPOLBEGFRESR1
SCHEMBL9495452 0.75 ESR1 (0.66) KMT2AGAAPOLBEGFRESR1
SCHEMBL28377376 0.75 KMT2A (0.66) KMT2AGAAPOLBEGFRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101143997-A Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH KK (JP) 2008-03-19 CN disclosed